Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of BAG3 in health and disease: A "Magic BAG of Tricks".

Journal of cellular biochemistry - 1 Jan 2022

Lin Heng, Koren Shon A, Cvetojevic Gregor, Girardi Peter, Johnson Gail V W

Abstract excerpt

The multi-domain structure of Bcl-2-associated athanogene 3 (BAG3) facilitates its interaction with many different proteins that participate in regulating a variety of biological pathways. After revisiting the BAG3 literature published over the past ten years with Citespace software, we classified the BAG3 research into several clusters, including cancer, cardiomyopathy, neurodegeneration, and viral propagation....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiomyopathies

Share to Myocytes, Cardiac

Share to Neoplasms

Share to Neurodegenerative Diseases

Share to Neurons

Share to Virus Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 33987872
DOI: 10.1002/jcb.29952
PMCID: PMC8590707

Genes

BAG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of BAG3 in health and disease: A "Magic BAG of Tricks".PMID 33987872Read ↗

Therapeutic targeting of BAG3: considering its complexity in cancer and heart disease.Semantic proximity Read ↗

Role of<i>BAG3</i>protein interactions in cardiomyopathiesSemantic proximity Read ↗

BAG3: a new player in the heart failure paradigm.Semantic proximity Read ↗

BAG Family Members as Mitophagy Regulators in MammalsSemantic proximity Read ↗

Advances in the role and mechanism of BAG3 in dilated cardiomyopathy.Semantic proximity Read ↗

A Bioinformatic Analysis of BAG Protein Interactors and Pathways in Alzheimer’s and Parkinson’s DiseaseSemantic proximity Read ↗

A common coding variant in BAG3 protects from heart failure.Semantic proximity Read ↗

BAG3-related myofibrillar myopathy: a further observation with cardiomyopathy at onset in pediatric age.Semantic proximity Read ↗

Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy.Semantic proximity Read ↗

A pan-cancer analysis of the oncogenic role of Bcl2-associated athanogene 2(BAG2) in human tumorsSemantic proximity Read ↗

Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the HeartSemantic proximity Read ↗

BAG3 protein controls B-chronic lymphocytic leukaemia cell apoptosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.