Article
Evolutionary cell biology traces the rise of the exomer complex in Fungi from an ancient eukaryotic component.
Scientific reports - 24 Jul 2018
Ramirez-Macias Inmaculada, Barlow Lael D, Anton Carlos, Spang Anne, Roncero Cesar, Dacks Joel B
Abstract excerpt
Cargo is transported from the trans-Golgi Network to the plasma membrane by adaptor complexes, which are pan-eukaryotic components. However, in yeast, cargo can also be exported by the exomer complex, a heterotetrameric protein complex consisting of two copies of Chs5, and any two members of four paralogous proteins (ChAPs). To understand the larger relevance of exomer, its phylogenetic distribution and function...
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