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Article

JEPEGMIX2: improved gene-level joint analysis of eQTLs in cosmopolitan cohorts.

Bioinformatics (Oxford, England) - 15 Jan 2018

Chatzinakos Chris, Lee Donghyung, Webb Bradley T, Vladimirov Vladimir I, Kendler Kenneth S, Bacanu Silviu-Alin

Abstract excerpt

Motivation: To increase detection power, researchers use gene level analysis methods to aggregate weak marker signals. Due to gene expression controlling biological processes, researchers proposed aggregating signals for expression Quantitative Trait Loci (eQTL). Most gene-level eQTL methods make statistical inferences based on (i) summary statistics from genome-wide association studies (GWAS) and (ii) linkage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28968763
DOI: 10.1093/bioinformatics/btx509
PMCID: PMC5860197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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