Article
Low variability at the HLA-E promoter region in the Brazilian population.
Human immunology - 1 Feb 2016
Veiga-Castelli Luciana Caricati, Bertuol João Marcos da Silveira Bulcão, Castelli Erick C, Donadi Eduardo Antonio
Abstract excerpt
Little information has been reported regarding the regulatory region of the HLA-E gene. Only a proximal segment (300 bp immediately before exon 1) has been described at IMGT/HLA database. We aimed to evaluate the genetic diversity of the promoter region by PCR amplification and DNA sequencing. We observed a pattern of sequencing interruption in the same position in all samples, suggesting the presence of a...
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