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Article

Apolipoprotein A-I Modulates Atherosclerosis Through Lymphatic Vessel-Dependent Mechanisms in Mice.

Journal of the American Heart Association - 22 Sept 2017

Milasan Andreea, Jean Gabriel, Dallaire François, Tardif Jean-Claude, Merhi Yahye, Sorci-Thomas Mary, Martel Catherine

Abstract excerpt

BACKGROUND: Subcutaneously injected lipid-free apoA-I (apolipoprotein A-I) reduces accumulation of lipid and immune cells within the aortic root of hypercholesterolemic mice without increasing high-density lipoprotein-cholesterol concentrations. Lymphatic vessels are now recognized as prerequisite players in the modulation of cholesterol removal from the artery wall in experimental conditions of plaque...

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Share to Aortic Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphatic Vessels

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Share to Plaque, Atherosclerotic

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Share to Vascular Endothelial Growth Factor Receptor-3

Source

Open in PubMed Open full text

Identifiers

PMID: 28939717
DOI: 10.1161/JAHA.117.006892
PMCID: PMC5634311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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