Article
Apolipoprotein A-I Limits the Negative Effect of Tumor Necrosis Factor on Lymphangiogenesis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2015
Bisoendial Radjesh, Tabet Fatiha, Tak Paul P, Petrides Francine, Cuesta Torres Luisa F, Hou Liming, Cook Adam, Barter Philip J, Weninger Wolfgang, Rye Kerry-Anne
Abstract excerpt
OBJECTIVE: Lymphatic endothelial dysfunction underlies the pathogenesis of many chronic inflammatory disorders. The proinflammatory cytokine tumor necrosis factor (TNF) is known for its role in disrupting the function of the lymphatic vasculature. This study investigates the ability of apolipoprotein (apo) A-I, the principal apolipoprotein of high-density lipoproteins, to preserve the normal function of lymphatic...
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