Article
Novel insights into the development of atherosclerosis in hemophilia A mouse models.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2011
Fabri D R, de Paula E V, Costa D S P, Annichino-Bizzacchi J M, Arruda V R
Abstract excerpt
BACKGROUND: Cardiovascular diseases in aging people with hemophilia (PWH) represent a growing concern. The underlying hypocoagulability probably provides a protective effect against acute thrombus formation, but the limited data available show no preventive effect against the development of atherogenesis in PWH. Atherosclerosis-prone mice are attractive tools for the study of atherosclerosis development, and may...
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