Association between interferon-induced helicase (IFIH1) rs1990760 polymorphism and seasonal variation in the onset of type 1 diabetes mellitus.

doi:10.1111/pedi.12569

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Article

Association between interferon-induced helicase (IFIH1) rs1990760 polymorphism and seasonal variation in the onset of type 1 diabetes mellitus.

Pediatric diabetes - 1 Mar 2018

Jermendy Ágnes, Szatmári Ildikó, Körner Anna, Szabó Attila J, Tóth-Heyn Péter, Hermann Róbert

Abstract excerpt

BACKGROUND: Infections, mostly of viral origin, may contribute to the seasonal variation in the onset of type 1 diabetes mellitus (T1DM). The rs1990760 (A>G, Ala946Thr) polymorphism (GG genotype) of the interferon induced helicase (IFIH1), a virus recognition receptor, confers a modest protection for T1DM. The aim of our study was to evaluate a possible association between this IFIH1 polymorphism and the seasonal...

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PMID: 28929635
DOI: 10.1111/pedi.12569

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IFIH1

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