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Article

The role of interferon induced with helicase C domain 1 (IFIH1) in the development of type 1 diabetes mellitus.

Arquivos brasileiros de endocrinologia e metabologia - 1 Dec 2013

Bouças Ana Paula, Oliveira Fernanda dos Santos de, Canani Luis Henrique, Crispim Daisy

Abstract excerpt

Type 1 diabetes mellitus (T1DM) is a chronic, progressive, autoimmune disease characterized by metabolic decompensation frequently leading to dehydration and ketoacidosis. Viral pathogens seem to play a major role in triggering the autoimmune destruction that leads to the development of T1DM. Among several viral strains investigated so far, enteroviruses have been consistently associated with T1DM in humans. One...

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Share to DEAD-box RNA Helicases
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to IFIH1 gene

Share to Genetic Predisposition to Disease

Share to Immunity, Innate

Share to Interferon-Induced Helicase, IFIH1

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 24402011
DOI: 10.1590/s0004-27302013000900001

Genes

IFIH1

Provenance

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