Article
The A allele of the rs1990760 polymorphism in the IFIH1 gene is associated with protection for arterial hypertension in type 1 diabetic patients and with expression of this gene in human mononuclear cells.
PloS one - 1 Jan 2013
Bouças Ana P, Brondani Letícia A, Souza Bianca M, Lemos Natália E, de Oliveira Fernanda S, Canani Luis H, Crispim Daisy
Abstract excerpt
BACKGROUND: The rs1990760 polymorphism of interferon induced with helicase C domain 1 (IFIH1) has been associated with type 1 diabetes mellitus (T1DM). Here, we investigated whether this polymorphism is associated with T1DM or its clinical characteristics in a Brazilian population, and if IFIH1 gene expression in mononuclear cells from T1DM patients differs according to the genotypes of this polymorphism. A...
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