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Article

An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes.

Diabetes - 1 Feb 2011

Winkler Christiane, Lauber Claudia, Adler Kerstin, Grallert Harald, Illig Thomas, Ziegler Anette-Gabriele, Bonifacio Ezio

Abstract excerpt

OBJECTIVE: Genome-wide association studies have identified gene regions associated with the development of type 1 diabetes. The aim of this study was to determine whether these associations are with the development of autoimmunity and/or progression to diabetes. RESEARCH DESIGN AND METHODS: Children (n = 1,650) of parents with type 1 diabetes were prospectively followed from birth (median follow-up 10.20 years)...

Read the complete abstract on PubMed

Topics

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Share to Autoantibodies
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DEAD-box RNA Helicases

Share to Diabetes Mellitus, Type 1

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Share to Enzyme-Linked Immunosorbent Assay

Share to Interferon-Induced Helicase, IFIH1

Share to Islets of Langerhans

Source

Open in PubMed Open full text

Identifiers

PMID: 21270278
DOI: 10.2337/db10-1269
PMCID: PMC3028371

Genes

IFIH1
ERBB3
PTPN2
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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