Article
The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations.
Diabetologia - 1 Jan 2010
Jermendy A, Szatmári I, Laine A P, Lukács K, Horváth K H, Körner A, Madácsy L, Veijola R, Simell O, Knip M, Ilonen J, Hermann R
Abstract excerpt
AIMS/HYPOTHESIS: The rs1990760 polymorphism (Ala946Thr) of interferon induced with helicase C domain 1 (IFIH1) has been proposed to associate with type 1 diabetes. In this study, association between IFIH1 Ala946Thr and type 1 diabetes was investigated in two distinct white populations, the Hungarians and Finns. METHODS: The rs1990760 polymorphism was genotyped in 757/509 Hungarian/Finnish childhood-onset cases,...
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