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Article

CRAMP deficiency leads to a pro-inflammatory phenotype and impaired phagocytosis after exposure to bacterial meningitis pathogens.

Cell communication and signaling : CCS - 16 Sept 2017

Kress Eugenia, Merres Julika, Albrecht Lea-Jessica, Hammerschmidt Sven, Pufe Thomas, Tauber Simone C, Brandenburg Lars-Ove

Abstract excerpt

BACKGROUND: Antimicrobial peptides are important components of the host defence with a broad range of functions including direct antimicrobial activity and modulation of inflammation. Lack of cathelin-related antimicrobial peptide (CRAMP) was associated with higher mortality and bacterial burden and impaired neutrophil granulocyte infiltration in a model of pneumococcal meningitis. The present study was designed...

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Identifiers

PMID: 28915816
DOI: 10.1186/s12964-017-0190-1
PMCID: PMC5602852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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