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Article

TLR2 and Caspase-8 Are Essential for Group B <i>Streptococcus</i> -Induced Apoptosis in Microglia

1 Nov 2007

Abstract excerpt

Microglia, the resident innate immune cells of the CNS, detect invading pathogens via various receptors, including the TLR. Microglia are involved in a number of neurodegenerative diseases in which their activation may be detrimental to neurons. It is largely unknown how this potentially deleterious action can be countered on a cellular level. We previously found that the interaction of TLR2 with group B...

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PMID: 17947688
DOI: 10.4049/jimmunol.179.9.6134

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