Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toll-like receptor 2 is partially involved in the activation of murine astrocytes by Streptococcus suis, an important zoonotic agent of meningitis.

Journal of neuroimmunology - 1 May 2011

Zheng Han, Punaro María C Domínguez, Segura Mariela, Lachance Claude, Rivest Serge, Xu Jianguo, Houde Mathieu, Gottschalk Marcelo

Abstract excerpt

The murine astrocyte response to virulent Streptococcus suis, a swine and an emerging human meningitis-causing pathogen, is reported. Albeit astrocytes do not internalize S. suis, all S. suis strains studied enhanced Toll-like receptor (TLR)2 expression and the production of pro-inflammatory cytokines and inducible nitric oxide synthase. Cell wall components and hemolysin (suilysin) are shown to be mainly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to Cerebral Cortex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glial Fibrillary Acidic Protein

Share to Microscopy, Confocal

Share to Nitric Oxide Synthase Type II

Share to Phagocytosis

Share to Streptococcus suis

Share to Toll-Like Receptor 2

Source

Identifiers

PMID: 21429596
DOI: 10.1016/j.jneuroim.2011.02.005

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toll-like receptor 2 is partially involved in the activation of murine astrocytes by Streptococcus suis, an important zoonotic agent of meningitis.PMID 21429596Read ↗

A Mechanism for Neurodegeneration Induced by Group B Streptococci through Activation of the TLR2/MyD88 Pathway in MicrogliaSemantic proximity Read ↗

SARS-CoV-2 Impact on the Central Nervous System: Are Astrocytes and Microglia Main Players or Merely Bystanders?Semantic proximity Read ↗

Two-Component Signal Transduction System VraSR Contributes to Neuroinflammation in Streptococcus Suis MeningitisSemantic proximity Read ↗

Innate immune recognition and inflammation in Neisseria meningitidis infectionSemantic proximity Read ↗

The Role of Macrophages in the Host’s Defense against Sporothrix schenckiiSemantic proximity Read ↗

TLR2 and Caspase-8 Are Essential for Group B <i>Streptococcus</i> -Induced Apoptosis in MicrogliaSemantic proximity Read ↗

TLR2-dependent recognition of Streptococcus suis is modulated by the presence of capsular polysaccharide which modifies macrophage responsivenessSemantic proximity Read ↗

Group B Streptococcal Infection and Activation of Human AstrocytesSemantic proximity Read ↗

Toll-like receptor 2 deficiency shifts PrP106-126-induced microglial activation from a neurotoxic to a neuroprotective phenotype.Semantic proximity Read ↗

Type I Interferon Induced by Streptococcus suis Serotype 2 is Strain-Dependent and May Be Beneficial for Host SurvivalSemantic proximity Read ↗

Toll-Like Receptors: Insights into Their Possible Role in the Pathogenesis of Lyme NeuroborreliosisSemantic proximity Read ↗

Induction and termination of inflammatory signaling in group B streptococcal sepsisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.