Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.

doi:10.1161/ATVBAHA.117.309768

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Article

Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017

Nakao Tetsushi, Horie Takahiro, Baba Osamu, Nishiga Masataka, Nishino Tomohiro, Izuhara Masayasu, Kuwabara Yasuhide, Nishi Hitoo, Usami Shunsuke, Nakazeki Fumiko, Ide Yuya, Koyama Satoshi, Kimura Masahiro, Sowa Naoya, Ohno Satoko, Aoki Hiroki, Hasegawa Koji, Sakamoto Kazuhisa, Minatoya Kenji, Kimura Takeshi, Ono Koh

Abstract excerpt

OBJECTIVE: Abdominal aortic aneurysm (AAA) is an increasingly prevalent and ultimately fatal disease with no effective pharmacological treatment. Because matrix degradation induced by vascular inflammation is the major pathophysiology of AAA, attenuation of this inflammation may improve its outcome. Previous studies suggested that miR-33 (microRNA-33) inhibition and genetic ablation of miR-33 increased serum...

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PMID: 28882868
DOI: 10.1161/ATVBAHA.117.309768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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