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Article

Vitamin D Receptor Activation Reduces Angiotensin-II-Induced Dissecting Abdominal Aortic Aneurysm in Apolipoprotein E-Knockout Mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2016

Martorell Sara, Hueso Luisa, Gonzalez-Navarro Herminia, Collado Aida, Sanz Maria-Jesus, Piqueras Laura

Abstract excerpt

OBJECTIVE: Abdominal aortic aneurysm (AAA) is a vascular disorder characterized by chronic inflammation of the aortic wall. Low concentrations of vitamin D3 are associated with AAA development; however, the potential direct effect of vitamin D3 on AAA remains unknown. This study evaluates the effect of oral treatment with the vitamin D3 receptor (VDR) ligand, calcitriol, on dissecting AAA induced by...

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Source

Identifiers

PMID: 27283745
DOI: 10.1161/ATVBAHA.116.307530

Genes

VDR
CCL2
CCL5
CXCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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