Article

IL-27 receptor signaling regulated stress myelopoiesis drives Abdominal Aortic Aneurysm development

2019-02-20

Abstract excerpt

Abdominal Aortic Aneurysm (AAA) is a vascular disease, where aortic wall degradation is mediated by accumulated immune cells. Though cytokines regulate the inflammatory milieu within the aortic wall, their contribution to AAA through distant alterations, particularly in the control of hematopoietic stem cells proliferation and myeloid cell differentiation remains poorly defined. Here we report an unexpected pathog...

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Literature Corpus work: 96f6305d-a809-5837-8f24-9849d43e08c9
DOI: 10.1101/555581

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