Article
Exploring the distribution of genetic markers of pharmacogenomics relevance in Brazilian and Mexican populations.
PloS one - 1 Jan 2014
Bonifaz-Peña Vania, Contreras Alejandra V, Struchiner Claudio Jose, Roela Rosimeire A, Furuya-Mazzotti Tatiane K, Chammas Roger, Rangel-Escareño Claudia, Uribe-Figueroa Laura, Gómez-Vázquez María José, McLeod Howard L, Hidalgo-Miranda Alfredo, Parra Esteban J, Fernández-López Juan Carlos, Suarez-Kurtz Guilherme
Abstract excerpt
Studies of pharmacogenomics-related traits are increasingly being performed to identify loci that affect either drug response or susceptibility to adverse drug reactions. However, the effect of the polymorphisms can differ in magnitude or be absent depending on the population being assessed. We used the Affymetrix Drug Metabolizing Enzymes and Transporters (DMET) Plus array to characterize the distribution of...
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