Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lessons from Cuba for Global Precision Medicine: CYP2D6 Genotype Is Not a Robust Predictor of CYP2D6 Ultrarapid Metabolism.

Omics : a journal of integrative biology - 1 Jan 2017

Dorado Pedro, González Idilio, Naranjo María Eugenia G, de Andrés Fernando, Peñas-Lledó Eva María, Calzadilla Luis Ramón, LLerena Adrián

Abstract excerpt

A long-standing question and dilemma in precision medicine is whether and to what extent genotyping or phenotyping drug metabolizing enzymes such as CYP2D6 can be used in real-life global clinical and societal settings. Although in an ideal world using both genotype and phenotype biomarkers are desirable, this is not always feasible for economic and practical reasons. Moreover, an additional barrier for clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cuba
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Healthy Volunteers

Share to Pharmacogenetics

Share to Phenotype

Share to Precision Medicine

Source

Identifiers

PMID: 28271978
DOI: 10.1089/omi.2016.0166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lessons from Cuba for Global Precision Medicine: CYP2D6 Genotype Is Not a Robust Predictor of CYP2D6 Ultrarapid Metabolism.PMID 28271978Read ↗

To Genotype or Phenotype for Personalized Medicine? CYP450 Drug Metabolizing Enzyme Genotype-Phenotype Concordance and Discordance in the Ecuadorian Population.Semantic proximity Read ↗

Interethnic variability of CYP2D6 alleles and of predicted and measured metabolic phenotypes across world populations.Semantic proximity Read ↗

Advancing CYP2D6 Pharmacogenetics through a Pharmacoequity Lens.Semantic proximity Read ↗

Interethnic Variability in CYP2D6, CYP2C9, and CYP2C19 Genes and Predicted Drug Metabolism Phenotypes Among 6060 Ibero- and Native Americans: RIBEF-CEIBA Consortium Report on Population Pharmacogenomics.Semantic proximity Read ↗

Clinical Relevance of CYP2D6 Polymorphisms in Patients of an Austrian Medical Practice: A Family Practice-Based Observational StudySemantic proximity Read ↗

High frequency of CYP2D6 ultrarapid metabolizers in Spain: controversy about their misclassification in worldwide population studies.Semantic proximity Read ↗

In vivo characterization of CYP2D6*12, *29 and *84 using dextromethorphan as a probe drug: a case report.Semantic proximity Read ↗

CYP2D6 pharmacogenetics and phenoconversion in personalized medicine.Semantic proximity Read ↗

The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction.Semantic proximity Read ↗

CYP450 Genotype/Phenotype Concordance in Mexican Amerindian Indigenous Populations-Where to from Here for Global Precision Medicine?Semantic proximity Read ↗

CYP2D6 phenotyping with dextromethorphan.Semantic proximity Read ↗

Cytochrome P450 2D6 polymorphism in eastern Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.