Article
Interethnic Variability in CYP2D6, CYP2C9, and CYP2C19 Genes and Predicted Drug Metabolism Phenotypes Among 6060 Ibero- and Native Americans: RIBEF-CEIBA Consortium Report on Population Pharmacogenomics.
Omics : a journal of integrative biology - 1 Sept 2018
Naranjo María-Eugenia G, Rodrigues-Soares Fernanda, Peñas-Lledó Eva M, Tarazona-Santos Eduardo, Fariñas Humberto, Rodeiro Idania, Terán Enrique, Grazina Manuela, Moya Graciela E, López-López Marisol, Sarmiento Alba P, Calzadilla Luis R, Ramírez-Roa Ronald, Ortiz-López Rocío, Estévez-Carrizo Francisco E, Sosa-Macías Martha, Barrantes Ramiro, LLerena Adrián
Abstract excerpt
Pharmacogenetic variation in Latin Americans is understudied, which sets a barrier for the goal of global precision medicine. The RIBEF-CEIBA Network Consortium was established to characterize interindividual and between population variations in CYP2D6, CYP2C9, and CYP2C19 drug metabolizing enzyme genotypes, which were subsequently utilized to catalog their "predicted drug metabolism phenotypes" across Native...
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