Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue.

G3 (Bethesda, Md.) - 5 Oct 2017

Sanchez Nicholas E, Harty Breanne L, O'Reilly-Pol Thomas, Ackerman Sarah D, Herbert Amy L, Holmgren Melanie, Johnson Stephen L, Gray Ryan S, Monk Kelly R

Abstract excerpt

As forward genetic screens in zebrafish become more common, the number of mutants that cannot be identified by gross morphology or through transgenic approaches, such as many nervous system defects, has also increased. Screening for these difficult-to-visualize phenotypes demands techniques such as whole-mount in situ hybridization (WISH) or antibody staining, which require tissue fixation. To date, fixed tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Zebrafish
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Polymorphism, Single Nucleotide

Share to Tissue Fixation

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 28855284
DOI: 10.1534/g3.117.300212
PMCID: PMC5633390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue.PMID 28855284Read ↗

Efficient mapping and cloning of mutations in zebrafish by low-coverage whole-genome sequencing.Semantic proximity Read ↗

RNA-seq-based mapping and candidate identification of mutations from forward genetic screens.Semantic proximity Read ↗

Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing.Semantic proximity Read ↗

MMAPPR: mutation mapping analysis pipeline for pooled RNA-seq.Semantic proximity Read ↗

Identification of mutations in zebrafish using next-generation sequencing.Semantic proximity Read ↗

Efficient mutation identification in zebrafish by microarray capturing and next generation sequencing.Semantic proximity Read ↗

Mutation mapping and identification by whole-genome sequencing.Semantic proximity Read ↗

Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy.Semantic proximity Read ↗

Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11.Semantic proximity Read ↗

Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing.Semantic proximity Read ↗

Combined haploid and insertional mutation screen in the zebrafish.Semantic proximity Read ↗

Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.