Article
MMAPPR: mutation mapping analysis pipeline for pooled RNA-seq.
Genome research - 1 Apr 2013
Hill Jonathon T, Demarest Bradley L, Bisgrove Brent W, Gorsi Bushra, Su Yi-Chu, Yost H Joseph
Abstract excerpt
Forward genetic screens in model organisms are vital for identifying novel genes essential for developmental or disease processes. One drawback of these screens is the labor-intensive and sometimes inconclusive process of mapping the causative mutation. To leverage high-throughput techniques to improve this mapping process, we have developed a Mutation Mapping Analysis Pipeline for Pooled RNA-seq (MMAPPR) that...
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