Article
The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases
1 Jan 2016
Abstract excerpt
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by excess B- and T-cell activation, the development of autoantibodies against self-antigens including nuclear antigens, and immune complex deposition in target organs, which triggers an inflammatory response and tissue damage. The genetic and environmental factors that contribute to the development of SLE have been studied...
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