Article
Review of Ets1 structure, function, and roles in immunity.
Cellular and molecular life sciences : CMLS - 1 Sept 2013
Garrett-Sinha Lee Ann
Abstract excerpt
The Ets1 transcription factor is a member of the Ets gene family and is highly conserved throughout evolution. Ets1 is known to regulate a number of important biological processes in normal cells and in tumors. In particular, Ets1 has been associated with regulation of immune cell function and with an aggressive behavior in tumors that express it at high levels. Here we review and summarize the general features...
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