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Article

Epigenetic Dysregulation in the Pathogenesis of Systemic Lupus Erythematosus

13 Jan 2024

Abstract excerpt

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease in which immune disorders lead to autoreactive immune responses and cause inflammation and tissue damage. Genetic and environmental factors have been shown to trigger SLE. Recent evidence has also demonstrated that epigenetic factors contribute to the pathogenesis of SLE. Epigenetic mechanisms play an important role in modulating the chromatin...

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PMID: 38256093
DOI: 10.3390/ijms25021019

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