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Article

Epigenetic mechanisms in lupus

5 May 2010

Abstract excerpt

PURPOSE OF REVIEW: Epigenetic mechanisms regulate gene expression, and epigenetic gene dysregulation is implicated in the pathogenesis of a growing number of disorders. Of the autoimmune diseases, epigenetic mechanisms are most clearly involved in human systemic lupus erythematosus (SLE). Herein, we summarize earlier work on epigenetic mechanisms contributing to human SLE. We first focus on the roles of DNA...

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PMID: 20445453
DOI: 10.1097/bor.0b013e32833ae915

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