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Article

Aberrant T cell ERK pathway signaling and chromatin structure in lupus.

Autoimmunity reviews - 1 Jan 2009

Gorelik Gabriela, Richardson Bruce

Abstract excerpt

Human systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibodies to nuclear components with subsequent immune complex formation and deposition in multiple organs. A combination of genetic and environmental factors is required for disease development, but how the environment interacts with the immune system in genetically predisposed hosts to cause lupus is unclear. Recent evidence...

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Share to Chromatin
Share to Chromatin Assembly and Disassembly
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Signal-Regulated MAP Kinases

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Source

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Identifiers

PMID: 18723128
DOI: 10.1016/j.autrev.2008.07.043
PMCID: PMC2642928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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