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Article

The Real Culprit in Systemic Lupus Erythematosus: Abnormal Epigenetic Regulation

15 May 2015

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease involving multiple organs and the presence of anti-nuclear antibodies. The pathogenesis of SLE has been intensively studied but remains far from clear. B and T lymphocyte abnormalities, dysregulation of apoptosis, defects in the clearance of apoptotic materials, and various genetic and epigenetic factors are attributed to the development of SLE. The...

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PMID: 25988383
DOI: 10.3390/ijms160511013

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