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Article

The dual nature of Ets-1: focus to the pathogenesis of systemic lupus erythematosus.

Autoimmunity reviews - 1 Jun 2011

Leng Rui-Xue, Pan Hai-Feng, Chen Gui-Mei, Feng Chen-Chen, Fan Yin-Guang, Ye Dong-Qing, Li Xiang-Pei

Abstract excerpt

E26 transformation-specific-1 (Ets-1) belongs to the Ets family of transcription factors which share a common 85-amino-acid DNA-binding domain. Ets-1 is essential to regulation of the immune system including immune cell proliferation and differentiation. Past data demonstrated Ets-1 play a role in negative regulation of Th17 cells and B cells differentiation. Recently, association of genetic variation in Ets-1...

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Source

Identifiers

PMID: 21296190
DOI: 10.1016/j.autrev.2011.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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