Article
Epigenetic Alterations in Immune Cells of Systemic Lupus Erythematosus and Therapeutic Implications.
Cells - 1 Feb 2022
Adams David E, Shao Wen-Hai
Abstract excerpt
Systemic lupus erythematosus (SLE) is an autoimmune disorder that is characterized by autoantibody production and dysregulated immune cell activation. Although the exact etiology of SLE remains unknown, genetic, hormonal, and complex environmental factors are known to be critical for pathologic immune activation. In addition to the inherited genetic predisposition, epigenetic processes that do not change the...
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