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Article

Mec1ATR is needed for extensive telomere elongation in response to ethanol in yeast.

Current genetics - 1 Feb 2018

Harari Yaniv, Kupiec Martin

Abstract excerpt

Telomere length homeostasis is essential for cell survival. In humans, telomeres shorten as a function of age. Short telomeres are known determinants of cell senescence and longevity. The yeast Saccharomyces cerevisiae expresses telomerase and maintains a strict telomere length homeostasis during vegetative growth. We have previously reported that different environmental signals promote changes in telomere length...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28780613
DOI: 10.1007/s00294-017-0728-1

Genes

ATM
ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mec1ATR is needed for extensive telomere elongation in response to ethanol in yeast.PMID 28780613Read ↗

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Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes.Semantic proximity Read ↗

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Telomerase, the recombination machinery and Rap1 play redundant roles in yeast telomere protection.Semantic proximity Read ↗

Yeast Rap1 contributes to genomic integrity by activating DNA damage repair genes.Semantic proximity Read ↗

A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenanceSemantic proximity Read ↗

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