Article
Genetic sharing with coronary artery disease identifies potential novel loci for bone mineral density.
Bone - 1 Oct 2017
Peng Cheng, Shen Jie, Lin Xu, Su Kuan-Jui, Greenbaum Jonathan, Zhu Wei, Lou Hui-Ling, Liu Feng, Zeng Chun-Ping, Deng Wei-Feng, Deng Hong-Wen
Abstract excerpt
Bone mineral density (BMD) is a complex trait with high missing heritability. Numerous evidences have shown that BMD variation has a relationship with coronary artery disease (CAD). This relationship may come from a common genetic basis called pleiotropy. By leveraging the pleiotropy with CAD, we may be able to improve the detection power of genetic variants associated with BMD. Using a recently developed...
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