Article
Bone mineral density and risk of breast cancer: A cohort study and Mendelian randomization analysis.
Cancer - 15 Jul 2022
Zhang Yanyu, Mao Xinhe, Yu Xingxing, Huang Xiaoxi, He Wei, Yang Haomin
Abstract excerpt
BACKGROUND: Estrogen is involved in both bone metabolism and breast cancer proliferation. However, evidence about the risk of breast cancer according to women's bone mineral density (BMD) is scarce, and little is known about their causal associations. METHODS: Women participating in the UK Biobank cohort were used to investigate the association between BMD and the risk of breast cancer using Cox regression...
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