Article
Brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism is associated with disease severity and incidence of cardiovascular events in a patient cohort.
American heart journal - 1 Aug 2017
Jiang Rong, Babyak Michael A, Brummett Beverly H, Hauser Elizabeth R, Shah Svati H, Becker Richard C, Siegler Ilene C, Singh Abanish, Haynes Carol, Chryst-Ladd Megan, Craig Damian M, Williams Redford B
Abstract excerpt
BACKGROUND: The rs6265 (Val66Met) single-nucleotide polymorphism in the BDNF gene has been related to a number of endophenotypes that have in turn been shown to confer risk for atherosclerotic cardiovascular disease (CVD). To date, however, very few studies have examined the association of the Val66Met single-nucleotide polymorphism with CVD clinical outcomes. METHODS: In a cohort of 5,510 Caucasian patients...
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