Article
Case-Only Survival Analysis Reveals Unique Effects of Genotype, Sex, and Coronary Disease Severity on Survivorship.
PloS one - 1 Jan 2016
Dungan Jennifer R, Qin Xuejun, Horne Benjamin D, Carlquist John F, Singh Abanish, Hurdle Melissa, Grass Elizabeth, Haynes Carol, Gregory Simon G, Shah Svati H, Hauser Elizabeth R, Kraus William E
Abstract excerpt
Survival bias may unduly impact genetic association with complex diseases; gene-specific survival effects may further complicate such investigations. Coronary artery disease (CAD) is a complex phenotype for which little is understood about gene-specific survival effects; yet, such information can offer insight into refining genetic associations, improving replications, and can provide candidate genes for both...
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