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Article

The T(-786)C endothelial nitric oxide synthase genotype predicts cardiovascular mortality in high-risk patients.

Journal of the American College of Cardiology - 19 Sept 2006

Rossi Gian Paolo, Maiolino Giuseppe, Zanchetta Mario, Sticchi Daniele, Pedon Luigi, Cesari Maurizio, Montemurro Domenico, De Toni Renzo, Zavattiero Silvia, Pessina Achille C

Abstract excerpt

OBJECTIVES: This study sought to investigate the impact of a common T(-786)C single-nucleotide polymorphism (SNP) in the promoter of the endothelial nitric oxide synthase (eNOS, NOS3) gene on cardiovascular (CV) death in a prospective cohort study. BACKGROUND: The T(-786)C SNP eNOS gene implies a blunted endothelium-dependent vasodilation in hypertensive patients and was associated with multivessel coronary...

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Identifiers

PMID: 16979000
DOI: 10.1016/j.jacc.2006.05.046

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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