Article
Genetic variant of BDNF (Val66Met) polymorphism attenuates stroke-induced angiogenic responses by enhancing anti-angiogenic mediator CD36 expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 Jan 2011
Qin Luye, Kim Eunhee, Ratan Rajiv, Lee Francis S, Cho Sunghee
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) has been shown to be necessary and sufficient for post-stroke recovery in rodents. From these observations, we and others have hypothesized that a common single nucleotide polymorphism (SNP) in the pro-domain of bdnf that leads to a methionine (Met) substi...
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