Impact of Brain-Derived Neurotrophic Factor (BDNF) Variants on Cardiometabolic Profiles: A Systematic Review and Meta-Analysis of Coronary Artery Disease and Obesity.

doi:10.1111/obr.70027

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Article

Impact of Brain-Derived Neurotrophic Factor (BDNF) Variants on Cardiometabolic Profiles: A Systematic Review and Meta-Analysis of Coronary Artery Disease and Obesity.

Obesity reviews : an official journal of the International Association for the Study of Obesity - 1 Feb 2026

Luo Zhi, Mei Yan, Qi Yi, Huang Ya, Wang Xiao, Chen Xiaoyan, Jiang Wencai

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF), a neurotrophin, plays a crucial role in neuronal survival and maintenance. Growing evidence suggests its potential involvement in the pathogenesis of coronary artery disease (CAD) and obesity. This study aims to investigate the effects of the BDNF nonsynonymous variant (rs6265) on cardiometabolic profiles, CAD risk, and obesity susceptibility. METHODS: PubMed,...

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Identifiers

PMID: 41067935
DOI: 10.1111/obr.70027

Genes

CAD
BDNF
DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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