Article
Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae.
PLoS genetics - 1 Jul 2017
Markowitz Tovah E, Suarez Daniel, Blitzblau Hannah G, Patel Neem J, Markhard Andrew L, MacQueen Amy J, Hochwagen Andreas
Abstract excerpt
Meiotic chromosomes assemble characteristic "axial element" structures that are essential for fertility and provide the chromosomal context for meiotic recombination, synapsis and checkpoint signaling. Whether these meiotic processes are equally dependent on axial element integrity has remained unclear. Here, we investigated this question in S. cerevisiae using the putative condensin allele ycs4S. We show that...
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