Article
Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior.
Molecular biology of the cell - 1 Feb 2002
Bhalla Needhi, Biggins Sue, Murray Andrew W
Abstract excerpt
The budding yeast YCS4 gene encodes a conserved regulatory subunit of the condensin complex. We isolated an allele of this gene in a screen for mutants defective in sister chromatid separation or segregation. The phenotype of the ycs4-1 mutant is similar to topoisomerase II mutants and distinct from the esp1-1 mutant: the topological resolution of sister chromatids is compromised in ycs4-1 despite normal removal...
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