Article
Separation of roles of Zip1 in meiosis revealed in heterozygous mutants of Saccharomyces cerevisiae.
Molecular genetics and genomics : MGG - 1 Nov 2009
Klutstein Michael, Xaver Martin, Shemesh Ronen, Zenvirth Drora, Klein Franz, Simchen Giora
Abstract excerpt
Synapsis of homologs during meiotic prophase I is associated with a protein complex built along the bivalents--the synaptonemal complex (SC). Mutations in the SC-component gene ZIP1 diminish SC formation, leading to reduced recombination levels and low spore viability. Here we show that in SK1 strains heterozygous for a deletion of ZIP1 in certain regions meiotic interference are impaired with no decrease in...
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