Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat.

doi:10.1161/01.hyp.37.2.456

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Article

Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2001

Cowley A W, Roman R J, Kaldunski M L, Dumas P, Dickhout J G, Greene A S, Jacob H J

Abstract excerpt

Consomic rats (SS.BN13), in which chromosome 13 from normotensive inbred Brown Norway rats from a colony maintained at the Medical College of Wisconsin (BN/Mcw) was introgressed into the background of Dahl salt-sensitive (SS/Mcw) rats, also maintained in a colony at the Medical College of Wisconsin, were bred. The present studies determined the mean arterial pressure (MAP) responses to salt and renal and...

Topics

Angiotensin II
Animals
Blood Pressure
Fibrosis
Furosemide
Gene Transfer Techniques
Genetic Therapy
Genotype
Hypertension
Kidney Glomerulus
Kidney Medulla

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kidney Tubules

Necrosis

Norepinephrine

Proteinuria

Rats

Rats, Inbred BN

Rats, Inbred Dahl

Source

Open in PubMed

Identifiers

PMID: 11230318
DOI: 10.1161/01.hyp.37.2.456

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