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Polymorphisms of CYP2C8, CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population.

Gene - 5 Sept 2017

Polonikov Alexey, Kharchenko Alexander, Bykanova Marina, Sirotina Svetlana, Ponomarenko Irina, Bocharova Anna, Vagaytseva Kseniya, Stepanov Vadim, Bushueva Olga, Churnosov Mikhail, Solodilova Maria

Abstract excerpt

Epoxyeicosatrienoic acids (EETs) are important vasoactive products of arachidonic acid metabolism with a wide range of biological actions in the cardiovascular system. The present study investigated whether single nucleotide polymorphisms (SNP) of genes coding cytochrome P450 2C subfamily, enzymes involved in biosynthesis of EETs, are associated with the risk of coronary heart disease (CHD). A total of 1255...

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Identifiers

PMID: 28687336
DOI: 10.1016/j.gene.2017.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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