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Article

Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction.

Pharmacogenetics - 1 Dec 2003

Yasar Umit, Bennet Anna M, Eliasson Erik, Lundgren Stefan, Wiman Björn, De Faire Ulf, Rane Anders

Abstract excerpt

SUMMARY: Cytochromes P450 (CYP) 2C8 and 2C9 are polymorphic enzymes responsible for the biosynthesis of vasoactive substances from arachidonic acid including endothelium-derived hyperpolarizing factor. Inter-individual differences in the action of these substances might be important in the pathogenesis of cardiovascular diseases such as acute myocardial infarction (AMI) and hypertension. This study describes the...

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Identifiers

PMID: 14646690
DOI: 10.1097/00008571-200312000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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