Article
Diplotypes of CYP2C9 gene is associated with coronary artery disease in the Xinjiang Han population for women in China.
Lipids in health and disease - 2 Sept 2014
Fu Zhenyan, Zhu Qing, Ma Yitong, Huang Ding, Pan Shuo, Xie Xiang, Liu Fen, Cha Erdenbat
Abstract excerpt
BACKGROUND: Cytochrome P450 (CYP) 2C9 is expressed in the vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which have the crucial role in the modulation of cardiovascular homeostasis. We sought to assess the association between the human CYP2C9 gene and coronary artery disease (CAD) in Xinjiang Han Population of China. METHODS: 301 CAD patients and 220...
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