Article
Association of interaction between smoking and CYP 2C19*3 polymorphism with coronary artery disease in a Uighur population.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Oct 2010
Yang Yi-Ning, Wang Xin-Lei, Ma Yi-Tong, Xie Xiang, Fu Zhen-Yan, Li Xiao-Mei, Chen Bang-Dang, Liu Fen
Abstract excerpt
OBJECTIVES: Cytochrome P450 (CYP) 2C19 is expressed in vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which are potent endogenous vasodilators and inhibitors of vascular inflammation. The purpose of this study is to explore the relationship between the interaction of CYP2C19*3 polymorphism and smoking and coronary artery disease (CAD) in a Uighur...
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