Article
A novel polymorphism of the CYP2J2 gene is associated with coronary artery disease in Uygur population in China.
Clinical biochemistry - 1 Aug 2013
Zhu Qing, Fu Zhenyan, Ma Yitong, Yang Hong, Huang Ding, Xie Xiang, Liu Fen, Zheng Yingying, Cha Erdenbat
Abstract excerpt
BACKGROUND: Cytochrome P450 (CYP) 2J2 is expressed in the vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs). The EETs are potent endogenous vasodilators and inhibitors of vascular inflammation. The aim of the present study was to assess the association between the human CYP2J2 gene polymorphism and coronary artery disease (CAD) in a Han and Uygur...
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