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Article

Experimental validation of the RATE tool for inferring HLA restrictions of T cell epitopes.

BMC immunology - 21 Jun 2017

Paul Sinu, Arlehamn Cecilia S Lindestam, Schulten Veronique, Westernberg Luise, Sidney John, Peters Bjoern, Sette Alessandro

Abstract excerpt

BACKGROUND: The RATE tool was recently developed to computationally infer the HLA restriction of given epitopes from immune response data of HLA typed subjects without additional cumbersome experimentation. RESULTS: Here, RATE was validated using experimentally defined restriction data from a set of 191 tuberculosis-derived epitopes and 63 healthy individuals with MTB infection from the Western Cape Region of...

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Identifiers

PMID: 28681704
DOI: 10.1186/s12865-017-0204-1
PMCID: PMC5499093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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