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Article

A population response analysis approach to assign class II HLA-epitope restrictions.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2015

Paul Sinu, Dillon Myles B C, Arlehamn Cecilia S Lindestam, Huang Huang, Davis Mark M, McKinney Denise M, Scriba Thomas Jens, Sidney John, Peters Bjoern, Sette Alessandro

Abstract excerpt

Identification of the specific HLA locus and allele presenting an epitope for recognition by specific TCRs (HLA restriction) is necessary to fully characterize the immune response to Ags. Experimental determination of HLA restriction is complex and technically challenging. As an alternative, the restricting HLA locus and allele can be inferred by genetic association, using response data in an HLA-typed...

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Identifiers

PMID: 25948811
DOI: 10.4049/jimmunol.1403074
PMCID: PMC4458389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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